Pharmaceutical plastic bottles are indispensable packaging bottles in the pharmaceutical industry. The general materials include PE, PP, PET, and so on. They have the advantages of not easy to break, good sealing performance, moisture-proof, sanitary, and meet the special requirements of pharmaceutical packaging. They can be directly used for pharmaceutical packaging without cleaning and drying. They are an excellent pharmaceutical packaging container, It is used for packaging oral solid drugs (such as tablets, capsules, granules, etc.) and oral liquid drugs (such as syrup, tincture, etc.). Compared with other plastic hollow packaging containers, plastic bottles for medicine have many special features.
Three key points to be understood in the design of plastic bottles for medicine.
1. Pharmaceutical plastic bottles are designed according to the principles and principles of affirmation in the design, which has effective application and design concept and ensures the performance advantages in application.
Most of the bottom of medicinal plastic bottles accept the convex bottom or flat bottom double round corner layout situation, because the middle of the convex bottom of the bottle bulges toward the inside of the bottle, forming an arch hole, which can increase the anti-internal pressure ability of the bottle body and ensure the stability of the factory bottle body. During injection molding, it can also prevent plastic collapse and make the thickness of the bottom of the bottle uniform, while the bottom layout of flat bottom and double rounded corners is mostly used for large-volume medical plastic bottles, which can better withstand the pressure from the inside of the bottle. The growth trend of shape and size is that the thread shape at the neck of small and medium-sized medicinal plastic bottles in injection blow molding originally grew from trapezoidal thread (single head) to semicircular multi-head fine thread.
This kind of bottle mouth thread situation is important for the good compatibility with the bottle cap, because the moisture resistance of the drug packaging depends largely on the common precision of the bottle mouth and the bottle cap, and here is an important part to reflect whether the sealing performance of the bottle mouth is good or bad.
2. A few days ago, most manufacturers have adopted Sichuan aluminum foil gasket at the U of medical plastic bottles for electromagnetic sealing, which has greatly increased the sealing performance of medical plastic bottles. From the profile of the neck and shoulder of a round plastic medicine bottle, its neck and shoulder are composed of two tangential circular radii, and are divided into two segments of a circular table rotator from the tangent point. The important factor affecting the strength of the bottle shoulder is the tilt angle of the bottle shoulder. When the shoulder is too flat, the bottle body is prone to collapse. If the shoulder length of the bottle here is 10mm, the tilt angle of the shoulder should be greater than 15 degrees, and the thickness of this part should not be less than 1mm (referring to the small bottle body).
3. After filling, plastic bottles for medicinal purposes should be capped by a capping machine with adjustable torque. The torque can be extracted according to the diameter of the cap according to the relevant dimensions. The size of the bottle and the cap is an important prerequisite for moisture and steam resistance, and the precision of the cap is the key to the moisture resistance results.
In order to ensure the safety of drugs, the sealing of the bottle mouth should be improved at first to increase the result of moisture resistance. The bottle wall is too thin to blow molding and has low strength. Generally, it is required that the wall thickness of other parts should be uniform except for the reinforcing rib at the bottle mouth and the thread part which is larger than the thickness of the bottle body. However, in order to improve the isolation and strength of plastic bottles for medicinal purposes, the design range of bottle body thickness is 1.5~2mm, and the current thickness tends to increase.